DONALD S. BURKE; ROBERT R. REDFIELD
BURKE DS, REDFIELD RR. Classification of Infections with Human Immunodeficiency Virus. Ann Intern Med. 1986;105:968. doi: 10.7326/0003-4819-105-6-968_1
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Published: Ann Intern Med. 1986;105(6):968.
To the editor: The original working case definition of the acquired immunodeficiency syndrome (AIDS) was designed by the Centers for Disease Control (CDC) to facilitate epidemiologic surveillance of the new epidemic. This definition contributed substantially to early scientific progress, including the discovery of the retroviral cause of AIDS. However, this restricted focus on the end-stage manifestations of human immunodeficiency virus (HIV) infection-that is, AIDS-has severely limited a full appreciation of the magnitude of the problem. As consultants who served on the CDC advisory committee, we believe that the recently published classification system for HIV infections (1) is an important advance.
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