NASSER M. GAYED, M.D.
To the editor: Rice and colleagues (1) state "There is . . . only a 5% chance that aminophylline causes a mean improvement of 115 mL or larger in the [forced expiratory volume in 1 second] FEV1." This statement is incorrect; it should read: "If aminophylline causes a mean improvement of 115 mL or larger in the FEV1, there would be only a 5% chance of obtaining results similar to ours (2)."
It seems that the analysis of the power of the test, referred to above, was done for the overall mean difference over the whole study. On the other
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GAYED NM. Aminophylline and Chronic Obstructive Pulmonary Disease. Ann Intern Med. 1988;108:307-308. doi: 10.7326/0003-4819-108-2-307_2
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Published: Ann Intern Med. 1988;108(2):307-308.
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