ROBERT F. RANDO, Ph.D.
In the past 6 years nucleic acid hybridization analysis has helped define more than 45 distinct types of human papillomaviruses. The classification of viral types is based
on the viral DNA sequence composition (genotype), rather than on viral structural antigenic features (serotype). A human papillomavirus genome is considered to represent a new viral type if its DNA sequence has less than 50% homology with the genomes of all other defined human papillomavirus types. Twelve of the more than 45 virus types have been found to be associated with anogenital tract lesions.
Due to intrinsic problems encountered when studying papillomaviruses, basic
Learn more about subscription options.
Register Now for a free account.
RANDO RF. Human Papillomavirus: Implications for Clinical Medicine. Ann Intern Med. 1988;108:628–630. doi: 10.7326/0003-4819-108-4-628
Download citation file:
Published: Ann Intern Med. 1988;108(4):628-630.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only