GEORGE T. HARRELL, M.D.
To the editor: Acute febrile cerebrovasculitis as reported by Wenzel and colleagues (1) and in a subsequent letter (2) poses a therapeutic dilemma to the clinician. No etiologic agent was recovered, and serologic data were confusing. Epidemiologic evidence suggested a possible rickettsial origin because the cases occurred in an area endemic for Rocky Mountain spotted fever, often of severe form.
My colleagues and I in Winston-Salem, North Carolina, studied a sizeable series of patients with rickettsial spotted fever beginning in 1941, before chemotherapy was available. We were among the first to use antibiotics in the disease. The patients were studied
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HARRELL GT. Acute Febrile Cerebrovasculitis. Ann Intern Med. 1987;106:479–480. doi: 10.7326/0003-4819-106-3-479_2
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Published: Ann Intern Med. 1987;106(3):479-480.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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