ROBERT G. TRAPP, M.D.
TRAPP RG. Cerebral Artery Vasoconstriction and the Raynaud Phenomenon. Ann Intern Med. 1987;106:630. doi: 10.7326/0003-4819-106-4-630_1
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Published: Ann Intern Med. 1987;106(4):630.
To the editor: Alexander and associates (1) show that patients with scleroderma and Raynaud phenomenon may also have cold-induced transient vasoconstriction of coronary arteries associated with abnormalities of myocardial function. Bulkley and coworkers (2) report the cases of nine patients with progressive systemic sclerosis and Raynaud phenomena who had sudden cardiac death and had normal coronary arteries at autopsy. Histologic study showed normal coronary arteries with focal thickening in only 10% of the small vessels. Other studies summarized by Alexander and associates (1) support further the concept that the well-known cutaneous manifestations of Raynaud phenomenon or disease may have a
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