HARRISON W. FARBER, M.D.; RAUL LAGUARDA, M.D.
FARBER HW, LAGUARDA R. Human Pulmonary Dirofilarial Infection. Ann Intern Med. 1987;106:777-778. doi: 10.7326/0003-4819-106-5-777_2
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Published: Ann Intern Med. 1987;106(5):777-778.
To the editor: As the geographic extent of infection with Dirofilaria immitis (canine heart worm) in the primary (canine) host has increased (1), so has the incidence of reported cases in the secondary (human) host (2-4). Because previous attempts at serologic diagnosis of human disease have been unreliable (2, 5), invasive procedures such as thoracotomy have been required to diagnose this innocuous entity. Although serologic methods, including enzyme-linked immunosorbent assay (ELISA) have been used routinely to diagnose canine infection (6, 7), their utility in diagnosing human disease has not been fully evaluated (4). We recently treated a patient in whom
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