LÁSZLÓ CZIRJAK, M.D.; GYULA SZEGEDI, M.D.
CZIRJAK L, SZEGEDI G. Benzene Exposure and Systemic Sclerosis. Ann Intern Med. 1987;107:118. doi: 10.7326/0003-4819-107-1-118_2
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Published: Ann Intern Med. 1987;107(1):118.
To the editor: A report of myelofibrosis, recently published by Hu (1) describes a case in which benzene was suspected to be the possible provoking agent of disease. Progressive systemic sclerosis is another disorder with pathologic fibrotic processes. We investigated the life history of our 61 patients with systemic sclerosis. Surprisingly, 17 female patients had been exposed to chemicals. In 3 of them, the provoking agent was suspected to be benzene (2-4). Furthermore, in 1 of our 3 patients with retroperitoneal fibrosis, the occupational exposure to benzene was also demonstrated. Our findings confirm the need for taking a thorough occupational
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