FRANÇOIS PARAF, M.D.; THIERRY POYNARD, M.D., Ph.D.; PIERRE BEDOSSA, M.D.; FRANCOIS GAYRAL, M.D.; SYLVIE NAVEAU, M.D.; JEAN-PIERRE PIGNON, M.D.; GUY LEMAIGRE, M.D.; JEAN-CLAUDE CHAPUT, M.D.
PARAF F, POYNARD T, BEDOSSA P, GAYRAL F, NAVEAU S, PIGNON J, et al. Adenocarcinoma of the Vater's Ampulla and von Recklinghausen Disease. Ann Intern Med. 1987;107:785. doi: 10.7326/0003-4819-107-5-785_1
Download citation file:
Published: Ann Intern Med. 1987;107(5):785.
To the editor: Sprengers and associates (1) report the first two cases of obstructive jaundice related to primary bile duct carcinoma in patients with von Recklinghausen disease. Carcinomas of the gastrointestinal tract, bile duct, and pancreas have been reported in association with neurofibromatosis, but seem under-represented in comparison with the general population (2). We report carcinoma of the Vater's ampulla in a patient with von Recklinghausen disease.
A 65-year-old man with known cutaneous neurofibromatosis was hospitalized because of painless jaundice. His total serum bilirubin level was 366 µmol/L and alkaline phosphatase level, 756 IU/L. Carcinoembryonic antigen level was not increased.
Learn more about subscription options.
Register Now for a free account.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only