LUCIO PATOIA, M.D.; ROBERTO GUERCIOLINI, M.D.; FRANCESCO MENICHETTI, M.D.; GlAMPAOLO BUCANEVE, M.D.; ALBANO DEL FAVERO, M.D.
PATOIA L, GUERCIOLINI R, MENICHETTI F, BUCANEVE G, DEL FAVERO A. Norfloxacin and Neutropenia. Ann Intern Med. 1987;107:788-789. doi: 10.7326/0003-4819-107-5-788_3
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Published: Ann Intern Med. 1987;107(5):788-789.
To the editor: Norfloxacin is a fluoro-quinolone used to treat urinary tract infections (1). Although decreased leukocyte or neutrophil counts have been reported in about 1% of patients receiving norfloxacin (2), single case reports documenting this type of side effect have not been published.
A 24-year-old woman was hospitalized because of anorexia nervosa. The biochemical analysis at admission showed slight normochromic normocytic anemia (hemoglobin, 12g/100 mL), normal leukocyte count (5600/mm3, with normal differential count), hypoalbuminemia (3g/100 mL), and raised alanine and aspartate aminotransferase levels (two to three times the normal values). No other laboratory abnormalities were seen.
Because of urinary
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