Jean-François Rossi, MD; Nathalie Fegueux, MD; Brigitte Calvet, MD; Wandrille Godefroy, MD
Rossi J, Fegueux N, Calvet B, Godefroy W. Alpha-Interferon in Angioimmunoblastic Lymphadenopathy. Ann Intern Med. 1988;109:512-513. doi: 10.7326/0003-4819-109-6-512
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Published: Ann Intern Med. 1988;109(6):512-513.
To the Editor: We read with interest the article on angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) (1). This disease is characterized by a clonal expansion of both B and T lymphocytes with expression of a particular histologic pattern. Treatment usually consists of corticosteroids or alkylating agents, resulting in a poor prognosis. Little is known about the effect of alpha-interferon in such a disease. Only one patient has been successfully treated with alpha-interferon (2). Alpha-interferon has been shown to be an effective treatment in some T-cell lymphopathies, such as epidermotropic T-cell lymphomas (3). We report the case of a patient with AILD
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