Joshua O. Benditt, MD; Harrison W. Farber, MD; Jonathan Wright, MD; Anand B. Karnad, MD
Benditt JO, Farber HW, Wright J, Karnad AB. Pulmonary Hemorrhage with Diffuse Alveolar Infiltrates in Men with High-Volume Choriocarcinoma. Ann Intern Med. 1988;109:674-675. doi: 10.7326/0003-4819-109-8-674
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Published: Ann Intern Med. 1988;109(8):674-675.
Choriocarcinoma in men, a rare tumor comprising less than 5% of germ cell tumors, is frequently associated with an elevated serum beta-human chorionic gonadotropin (B-HCG) level. Despite high cure rates reported in men with advanced germ cell tumors of the testis, patients with choriocarcinoma and markedly elevated B-HCG levels (> 50 000 mIU/mL) continue to have a poor prognosis (1-3). Choriocarcinoma is a hemorrhagic tumor, and complications from bleeding at the primary or metastatic site may contribute significantly to the poor prognosis (1, 4).
Hemorrhagic complications in women with choriocarcinoma have been well described (5-7); however, similar complications in men
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Hematology/Oncology, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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