Kenneth E. Sherman, PhD, MD; Michael Bornemann, MD
Sherman K., Bornemann M.; Amitriptyline and Asymptomatic Hypoglycemia. Ann Intern Med. 1988;109:683-684. doi: 10.7326/0003-4819-109-8-683_2
Download citation file:
Published: Ann Intern Med. 1988;109(8):683-684.
To the Editor: Hypoglycemic unawareness may occur in diabetic patients with autonomic neuropathy or during treatment with beta-adrenergic blockers. Tricyclic antidepressants are frequently given to diabetic patients to treat peripheral neuropathy or depression, or both, and have not been reported to cause hypoglycemic unawareness. We describe a case of hypoglycemic unawareness in a patient with type I diabetes mellitus receiving treatment with amitriptyline whose symptoms resolved after the medication was withdrawn.
A 24-year-old woman who had had type I diabetes mellitus for 8 years, complicated by frequent episodes of ketoacidosis, proliferative retinopathy, and bilateral lumbar sympathectomy for reflex sympathetic dystrophy,
to gain full access to the content and tools.
Learn more about subscription options.
Register Now for a free account.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only