Beth Conover, RN, MS; Jonathan C. Goldsmith, MD; Bruce A. Buehler, MD; Pierre A. Maloley, PharmD; Mary L. Windle, PharmD
Pentamidine isethionate is an aromatic diamidine-derivative antiprotazoal agent now being used in treating Pneumocystis carinii pneumonia in patients with immunodeficient disease states (1). The agent is usually administered by the intravenous or intramuscular route. Clinicians, however, have used aerosol preparations in an effort to target the respiratory tract during treatment and to decrease systemic side effects (2, 3). This route of administration presents health care providers with the potential for exposure to pentamidine, and concerns have been expressed that pregnant staff members might have associated adverse reproductive effects.
The Nebraska Teratogen Project addressed this concern, and unfortunately, little information is
Learn more about subscription options.
Register Now for a free account.
Conover B, Goldsmith JC, Buehler BA, Maloley PA, Windle ML. Aerosolized Pentamidine and Pregnancy. Ann Intern Med. 1988;109:927. doi: 10.7326/0003-4819-109-11-927_1
Download citation file:
Published: Ann Intern Med. 1988;109(11):927.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only