Anne Francois, MD; Marc Freund, MD; Fernand Daffos, MD; Philippe Remy, MD; Martine Aiach, MD; Christian Jacquot, MD
Francois A, Freund M, Daffos F, Remy P, Aiach M, Jacquot C. Repeated Fetal Losses and the Lupus Anticoagulant. Ann Intern Med. 1988;109:993-994. doi: 10.7326/0003-4819-109-12-993
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Published: Ann Intern Med. 1988;109(12):993-994.
To the Editor: Combined therapy with prednisone and low doses of aspirin has been reported to reduce the risk for fetal loss in women with the lupus anticoagulant (1, 2). We report a case in which a woman with the lupus anticoagulant had had three successive fetal losses while receiving this combined therapy. The outcome of a fourth pregnancy was favorable when she was given high-dose intravenous polyvalent immunoglobulin therapy.
A 24-year-old woman had episodes of deep venous thrombosis and pulmonary embolism when she was 18, 19, and 22 years of age. She was found to have the lupus anticoagulant
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