Ann Parke, MBBS; Donald Maier, MD; Daniel Wilson, BA; John Andreoli, MD; Mark Ballow, MD
Parke A, Maier D, Wilson D, Andreoli J, Ballow M. Intravenous Gamma-Globulin, Antiphospholipid Antibodies, and Pregnancy. Ann Intern Med. 1989;110:495-496. doi: 10.7326/0003-4819-110-6-495_2
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Published: Ann Intern Med. 1989;110(6):495-496.
To the Editor: In their letter ( 1 ) on the use of intravenous immunoglobulin therapy (IVIG) in pregnant women with antiphospholipid antibodies and a history of fetal loss, Francois and colleagues suggest that IVIG may be the safest therapy to use in such women. From our experience with a young woman with the primary antiphospholipid antibody syndrome, we agree with their recommendation.
In a 29-year-old white woman who previously had five spontaneous abortions, a full gynecologic examination failed to show any cause for her recurrent abortions. Tests for autoantibodies, including antiphospholipid (APL) antibodies, indicated the presence of numerous autoantibodies,
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