Alan G. Barbour, MD
Lyme disease, or, as it is increasingly called, Lyme borreliosis, is currently the commonest arthropodborne infection in the United States and Europe (1, 2). It also appears to be a frequent zoonotic disease in the Soviet Union (3). The etiologic agent, Borrelia burgdorferi, is a spirochete that is transmitted from animal to animal by hard-bodied ticks of the genus Ixodes (4). For humans, who are inadvertent hosts for the ticks, Lyme borreliosis may be brief and inconsequential or chronic and disabling (5-7). Major manifestations in the skin, joints, or nervous system of some patients can evolve over years. The inflammation
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Barbour AG. The Diagnosis of Lyme Disease: Rewards and Perils. Ann Intern Med. 1989;110:501-502. doi: 10.7326/0003-4819-110-7-501
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Published: Ann Intern Med. 1989;110(7):501-502.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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