Evangelos A. Akriviadis, MD; Allan G. Redeker, MD
Akriviadis EA, Redeker AG. Fulminant Hepatitis A in Intravenous Drug Users with Chronic Liver Disease. Ann Intern Med. 1989;110:838-839. doi: 10.7326/0003-4819-110-10-838
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Published: Ann Intern Med. 1989;110(10):838-839.
Fulminant hepatitis is a rare complication of acute hepatitis A infection, with an estimated case fatality rate of 0.14% among hospitalized patients (1). Hepatitis A is transmitted primarily by the fecal-oral route (1). There has been an increased incidence of hepatitis A infection among intravenous drug users (2-5), and percutaneous transmission has been established in animals (6) and in humans (7-9). Whether mode of transmission and preexistent liver disease alter the usually benign course of hepatitis A infection is not known.
We report here four cases of fulminant hepatic failure associated with hepatitis A infection encountered in intravenous drug users
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Gastroenterology/Hepatology, Liver Disease, Tobacco, Alcohol, and Other Substance Abuse.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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