Louis A. VanderMolen, MD; John W. Smith, MD; Dan L. Longo, MD; Ronald G. Steis, MD; Peter Kremers, MD; Mario Sznol, MD
VanderMolen L., Smith J., Longo D., Steis R., Kremers P., Sznol M.; Adrenal Insufficiency and Interleukin-2 Therapy. Ann Intern Med. 1989;111:185. doi: 10.7326/0003-4819-111-2-185_1
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Published: Ann Intern Med. 1989;111(2):185.
To the Editor: Rao and colleagues (1) recently reviewed bilateral massive adrenal hemorrhage; however, its occurrence during interleukin-2 therapy has not been reported.
A 52-year-old man developed right flank pain in October 1987. He had a normal blood pressure without orthostatic changes. Cardiac, pulmonary, and neurologic examinations were normal. An abdominal computed tomographic (CT) scan revealed an 11.4 X 9.6 cm right renal mass with direct extension into the liver, ablation and involvement of the right adrenal gland, and metastasis to the left adrenal gland. Results of a routine biochemical profile, complete blood count, and differential cell count were normal.
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