J.C. Gallagher, MD; B.L. Riggs, MD
To the Editor: In a double-blind, randomized, placebo-controlled 2-year clinical trial reported in a recent issue, Ott and Chesnut (1) concluded that "calcitriol treatment is not effective in postmenopausal osteoporosis." We disagree. Whereas the authors are to be commended for a comprehensive and well-done clinical trial, we believe that their results are applicable only to the conditions of their study and should not be generalized.
Their study was part of a three-center trial that was run according to a common basic protocol. Both Aloia and colleagues (2) and Gallagher and colleagues (3), from the other participating centers, reported that calcitriol
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Gallagher J, Riggs B. Calcitriol for Postmenopausal Osteoporosis. Ann Intern Med. 1989;111:621. doi: 10.7326/0003-4819-111-7-621_1
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Published: Ann Intern Med. 1989;111(7):621.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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