Irene H. Grant, MD; Jonathan W.M. Gold, MD; Murray Wittner, MD, PhD; Herbert B. Tanowitz, MD; Carl Nathan, MD; Klaus Mayer, MD; Lillian Reich, MD; Norma Wollner, MD; Laurel Steinherz, MD; Fereshteh Ghavimi, MD; Richard J. O'Reilly, MD; Donald Armstrong, MD
Grant IH, Gold JW, Wittner M, Tanowitz HB, Nathan C, Mayer K, et al. Transfusion-Associated Acute Chagas Disease Acquired in the United States. Ann Intern Med. 1989;111:849-851. doi: 10.7326/0003-4819-111-10-849
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Published: Ann Intern Med. 1989;111(10):849-851.
Although a significant problem in Latin America (1), the transmission of Trypanosoma cruzi infection by transfusion has not been unequivocally documented in the United States. We report a case of severe acute transfusion-acquired Chagas disease in a child with Hodgkin disease who had never travelled to an endemic area; however, she had received platelets from an asymptomatic Bolivian immigrant who had serologic evidence of T. cruzi infection.
An 11-year-old white girl with Hodgkin disease who had been in remission since May 1987 after splenectomy, radiotherapy, and chemotherapy presented in April 1988 with a temperature of 38.3 °C. Her physical examination
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