Peter Nickerson, MD; Pamela Orr, MD; Maria-Louise Schroeder, MD; Leila Sekla, MD; James B. Johnston, MD
Opportunistic infections have become a major cause of morbidity in the immunocompromised host. In patients with neutropenia, such infections often arise from their own indigenous flora; however, another potential mode of infection is the transmission of blood-borne organisms by transfusions. Patients with granulocytopenia who receive multiple blood products during chemotherapy are especially prone to transfusion-associated infections. We describe the first case of transfusion-associated acute Chagas disease in a nonendemic area of North America.
In June 1986, a 1-year-old infant presented with a cerebral thrombosis and was subsequently found to have protein S deficiency. When the family was screened,
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Nickerson P, Orr P, Schroeder M, Sekla L, Johnston JB. Transfusion-Associated Trypanosoma cruzi Infection in a Non-Endemic Area. Ann Intern Med. 1989;111:851-853. doi: 10.7326/0003-4819-111-10-851
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Published: Ann Intern Med. 1989;111(10):851-853.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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