Esther Granot, MD; David Raveh, MD; Rami Eliakim, MD
To the Editor: Vitamin E deficiency resulting from prolonged fat malabsorption is associated with a progressive neuromyopathy and ophthalmoplegia. In abetalipoproteinemia, retinopathy and neurologic manifestations may be prevented by vitamin E supplementation (1). In infants with very low birthweight, vitamin E deficiency may present as hemolytic anemia and edema (2). Vitamin E deficiency has not been implicated as a cause of edema in any other age group.
We recently treated a 32-year-old woman who had had bilateral asymmetrical pitting edema of the lower limbs since 17 years of age. Blood protein levels, cardiac studies, Doppler venous recordings, and thyroid function
Learn more about subscription options.
Register Now for a free account.
Granot E, Raveh D, Eliakim R. Vitamin E Deficiency and Peripheral Edema. Ann Intern Med. 1989;111:859. doi: 10.7326/0003-4819-111-10-859_1
Download citation file:
Published: Ann Intern Med. 1989;111(10):859.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only