Charles B. Payne, MD; Helen E. Sloan, MD
To the Editor: The chronic fatigue syndrome has received considerable attention since its appearance approximately 4 years ago. Reports have focused on the immunologic evidence of Epstein-Barr virus infection in the pathogenesis of the syndrome. A working case definition was recently published (1). We have studied a 35-year-old woman who had the persistent symptoms of exertional dyspnea, malaise, and the inability to work because of a febrile "viral" illness that had presented about 6 months previously and was initially associated with muscle weakness and cough. Her symptoms met the working definition of the syndrome. On 27 February 1989, her quantitative
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Payne CB, Sloan HE. Pulmonary Function and the Chronic Fatigue Syndrome. Ann Intern Med. 1989;111:860. doi: 10.7326/0003-4819-111-10-860_1
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Published: Ann Intern Med. 1989;111(10):860.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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