Norman D. Grace, MD
Bleeding from esophageal varices continues to be a major complication of cirrhosis and portal hypertension, with the mortality for a bleeding episode close to 50% (1). Although the risk for first hemorrhage after discovery of esophageal varices is 25% to 30%, the risk for recurrent variceal hemorrhage after control of the initial bleeding episode is close to 70% (2). Most episodes of recurrent hemorrhage occur within 1 year of the initial episode. Because of the high morbidity associated with variceal bleeding, there is considerable interest in finding a therapy that will both prevent variceal bleeding and improve survival.
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Grace ND. Prevention of Recurrent Variceal Bleeding—Is Surgical Rescue the Answer?. Ann Intern Med. 1990;112:242–244. doi: 10.7326/0003-4819-112-4-242
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Published: Ann Intern Med. 1990;112(4):242-244.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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