Marin H. Kollef, MD; Michael T. McCormack, MD; William E. Caras, MD; Vishnu V.B. Reddy, MD; David Bacon, MD
Kollef MH, McCormack MT, Caras WE, Reddy VV, Bacon D. The Fat Overload Syndrome: Successful Treatment with Plasma Exchange. Ann Intern Med. 1990;112:545-546. doi: 10.7326/0003-4819-112-7-545
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Published: Ann Intern Med. 1990;112(7):545-546.
The fat overload syndrome is a rare complication of the intravenous administration of fat emulsion. It is characterized by sudden elevation of the serum triglyceride level associated with fever, hepatosplenomegaly, coagulopathy, and variable end-organ dysfunction (1-3). Specific successful therapy other than supportive care for the fat overload syndrome has not been described. We report the first successful use of plasma exchange in treating this condition.
A 39-year-old man was admitted to a community hospital for an exacerbation of his long-standing asthma. He was treated with intravenous theophylline, erythromycin, and nebulized metaproterenol. On the second hospital day, supplemental parenteral
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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