Pietro Martino, MD; Giovanna Meloni, MD; Antonio Cassone, MD
To the Editor: The use of colony-stimulating factors associated with conventional antifungal therapy has recently been advocated to treat systemic fungal infections (1). We report the first case, to our knowledge, of catheter-related right-sided mural candidal endocarditis treated with fluconazole in association with recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF).
A 40-year-old man with acute nonlymphoid leukemia in first complete remission was hospitalized in July 1988 for autologous bone marrow transplantation. Six days after bone marrow infusion, the patient developed a fever and staphylococcal septicemia that subsided only after removal of the Hickman catheter. On day 14 after bone marrow infusion the
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Martino P, Meloni G, Cassone A. Candidal Endocarditis and Treatment with Fluconazole and Granulocyte-Macrophage Colony-Stimulating Factor. Ann Intern Med. 1990;112:966-967. doi: 10.7326/0003-4819-112-12-966_2
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Published: Ann Intern Med. 1990;112(12):966-967.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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