Elias Abrutyn, MD
This issue contains a preliminary report (1) describing a possible beneficial effect of extracorporeal photopheresis in patients with the acquired immunodeficiency syndrome (AIDS)-related complex. The justification for the experiment was the known inactivating effect of psoralens and long-wavelength ultraviolet A light on both DNA and RNA viruses, including human immunodeficiency virus (HIV) (2). In addition, photopheresis was found recently to be beneficial in the treatment of cutaneous T-cell lymphoma, a CD4 cell tumor (3).
As described in the report by Bisaccia and colleagues (1), patients were given the photosensitizer, 8-methoxypsoralen, orally; 2 hours later, after absorption and distribution of the
Learn more about subscription options.
Register Now for a free account.
Abrutyn E. Photopheresis and Human Immunodeficiency Virus (HIV) Infection: The
Annals Views Preliminary Reports. Ann Intern Med. 1990;113:263-264. doi: 10.7326/0003-4819-113-4-263
Download citation file:
Published: Ann Intern Med. 1990;113(4):263-264.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only