Gregg E. Davies, MD; Douglas A. Triplett, MD
Antiphospholipid antibodies may be found in patients with various diseases, especially in those with systemic lupus erythematosus, or in patients without any apparent predisposing condition. The presence of antiphospholipid antibodies in patients with systemic lupus erythematosus is significantly associated with venous or arterial thromboembolism, neurologic disorders, and thrombocytopenia (1). In patients without systemic lupus erythematosus, an association between antiphospholipid antibodies and thromboembolic or other disorders has been strongly suspected but not conclusively proved (2, 3). We describe a patient with antiphospholipid antibodies and thrombocytopenia who twice developed the blue toe syndrome after receiving treatment with prednisone to increase the platelet
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Davies GE, Triplett DA. Corticosteroid-Associated Blue Toe Syndrome: Role of Antiphospholipid Antibodies. Ann Intern Med. 1990;113:893–895. doi: 10.7326/0003-4819-113-11-893
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Published: Ann Intern Med. 1990;113(11):893-895.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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