Steven Snyder, MD
Snyder S. Metoprolol-Induced Polymyalgia-Like Syndrome. Ann Intern Med. 1991;114:96-97. doi: 10.7326/0003-4819-114-1-96_2
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Published: Ann Intern Med. 1991;114(1):96-97.
To the Editors: Common side effects of metoprolol and other beta adrenergic-receptor blocking agents (beta blockers) include bradycardia, exacerbation of congestive heart failure, bronchospasm, and attenuation of physiologic responses to hypoglycemia (1). Vasculitis and other rheumatic syndromes, aside from exacerbation of Raynaud phenomenon, are uncommon but potential side effects (1-4). I describe the case history of a patient with a severe polymyalgia rheumatica-like syndrome associated with metoprolol use.
In 1987, a 60-year-old white man presented with a 1-month history of bilateral upper leg myalgias, anorexia, and fatigue. He had a history of hypertension for which he had taken metoprolol, 100
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Cardiology, Nephrology, Hypertension, Coronary Risk Factors.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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