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Physiologists did not acknowledge intestinal secretion as a cause of diarrhea until the late 1960s. The clinical and experimental studies of cholera conducted in the past 20 years have clearly established intestinal fluid and electrolyte secretion as an important physiologic process. Subsequently, the role of intestinal fluid and electrolyte secretion has been emphasized as a critical determinant for diarrhea. Although several excellent textbooks presently address the physiology of the gastrointestinal tract and the pathophysiology of gastrointestinal disease, only minor sections within these textbooks have been devoted to the issues of intestinal secretion and secretory diarrhea. This text, with 53 contributors,
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Textbook of Secretory Diarrhea. Ann Intern Med. 1991;114:917. doi: 10.7326/0003-4819-114-10-917_5
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Published: Ann Intern Med. 1991;114(10):917.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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