Michael J. Henry, MD
Henry MJ. Theophylline or Physician Toxicity?. Ann Intern Med. 1991;115:407-408. doi: 10.7326/0003-4819-115-5-407
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Published: Ann Intern Med. 1991;115(5):407-408.
To the Editors: Schiff and colleagues' report (1) on preventable factors in inpatient theophylline toxicity documents the many circumstances that may contribute to the development of theophylline toxicity. Also documented are the negligence or incompetence of the responsible physicians at Cook County Hospital. Being a "busy physician" is no excuse for 1) ordering a drug level but failing to check the result; 2) failing to consider factors predisposing to theophylline toxicity (for example, heart failure, liver disease, or coadministration of drugs known to decrease theophylline clearance) when determining dosage; 3) failing to consider drug toxicity in a patient developing psychosis
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