Ian Joffe, MD
To the editors: Kadunce and colleagues (1) report that cigarette smoking is an independent risk factor for the development of facial wrinkles, although the mechanism is unclear. As noted by the authors, only a subgroup of subjects (27.5%) with a smoking history of more than 50 pack-years were severely wrinkled, a relation similar to that between smoking and chronic obstructive pulmonary disease, in which only 26% of heavy smokers developed airway obstruction. An inverse relation has been reported among vitamin A consumption, retinol levels, and the subsequent development of lung cancer in men (2). Smoking might contribute to the increased
Learn more about subscription options.
Register Now for a free account.
Joffe I. Cigarette Smoking and Facial Wrinkling. Ann Intern Med. 1991;115:659-660. doi: 10.7326/0003-4819-115-8-659
Download citation file:
Published: Ann Intern Med. 1991;115(8):659-660.
Cardiology, Coronary Risk Factors, Smoking, Tobacco, Alcohol, and Other Substance Abuse.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only