D. H. Vesole, MD, PhD; S. Jagannath, MD
To the Editors: Spitzer, Zwiebel and Jacobson (1) recently reported the case of a patient who received an HLA-identical bone marrow transplant after receiving a renal allograft from the same donor. The patient developed severe graft-versushost disease with persistent leukemia and died 40 days after transplantation. We report a similar instance of grade-Ill graftversus-host disease treated successfully.
A 37-year-old white man with end-stage renal disease secondary to rapidly progressive glomerulonephritis had a kidney transplant from an HLA-identical sibling donor on 31 July 1980. The patient received azathioprine and prednisone therapy until September 1988, when he developed pancytopenia. The azathioprine therapy
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Vesole DH, Jagannath S. Transplants from the Same Donor. Ann Intern Med. 1992;116:269–270. doi: 10.7326/0003-4819-116-3-269
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Published: Ann Intern Med. 1992;116(3):269-270.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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