Nortin M. Hadler, MD
Osteoarthritis is a well-defined pathoanatomic entity readily demonstrable by modern imaging techniques. For a century, the pathology that is this disease has been ingrained in the mind of every medical student: inexorable progression from subtle biochemical alterations in articular cartilage through cartilage loss and reactive bone formation to the end-stage of eburnated bone and exuberant osteophytosis. We all shudder at the image of the patient suffering with end-stage osteoarthritis, bedeviled by a deformed, unstable, incapacitating, and painful knee. What physician can listen to the complaint of knee pain without conjuring up the image of such an outcome? What physician can
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Hadler NM. Knee Pain Is the Malady—Not Osteoarthritis. Ann Intern Med. 1992;116:598–599. doi: 10.7326/0003-4819-116-7-598
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Published: Ann Intern Med. 1992;116(7):598-599.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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