Ali Serdar Fak, MD; Cetin Ozener, MD; Emel Akoglu, MD
Fak AS, Ozener C, Akoglu E. Colchicine and Secondary Amyloidosis. Ann Intern Med. 1992;117:795-796. doi: 10.7326/0003-4819-117-9-795_3
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Published: Ann Intern Med. 1992;117(9):795-796.
To the Editors: We are writing to support the observations in the letter by Zemer and Langevitz that secondary amyloidosis could be treated with colchicine (1).
We have followed a 52-year-old man with psoriatic arthritis for more than 10 years. He presented with skin rashes, deforming arthritis, mild uremia, and peripheral edema. His 24-hour urinary protein excretion was 2 g, and his creatinine clearance was 30 mL/minute. Renal biopsy showed amyloidosis, and he was started on topical agents for his skin rashes and on colchicine for amyloidosis. Thirty months later, peripheral edema and protenuria regressed. Serum creatinine and blood urea
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