Jennie R. Crews, MD; J. Kevin Harrison, MD; G. Ralph Corey, MD; Charles Steenbergen, MD, PhD; Thomas M. Bashore, MD
Crews JR, Harrison JK, Corey GR, Steenbergen C, Bashore TM. Stunned Myocardium in the Toxic Shock Syndrome. Ann Intern Med. 1992;117:912-913. doi: 10.7326/0003-4819-117-11-912
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Published: Ann Intern Med. 1992;117(11):912-913.
Although it is not commonly recognized, myocardial dysfunction in the toxic shock syndrome may be severe, even life-threatening (1, 2). The cause of this acute cardiomyopathy remains unclear. Clinically, left ventricular dysfunction in the toxic shock syndrome has been reversible, similar to prolonged but transient postischemic myocardial dysfunction, a process termed "stunned myocardium" (3). Cardiac histopathologic findings in the toxic shock syndrome are limited to autopsy data, and the pathologic changes seen have been modest compared with the clinical severity of left ventricular dysfunction (4, 5). We report the first premortem cardiac histologic findings in a patient with severe, acute
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Cardiology, Pulmonary/Critical Care, Multi-Organ Failure and Sepsis, Acute Coronary Syndromes, Coronary Heart Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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