Corrado Girmenia, MD; Vittorio Donato, MD; Anna Paola Iori, MD; Pietro Martino, MD
Two patients with leukemia, who underwent remission induction chemotherapy and allogeneic bone marrow transplantation, respectively, reported chest pain and dyspnea after recovery from neutropenia. In both patients, chest radiographs showed only a pneumothorax, whereas computed tomographic scanning also showed a peripheral pseudomycetoma. Antifungal treatment was instituted. The occurrence of spontaneous pneumothorax in patients with hematologic malignancies, particularly after recovery from neutropenia, may indicate the presence of a subpleural infection. Computed tomographic scanning can reveal peripheral pulmonary lesions that are not detected by chest roentgenography.
Girmenia C, Donato V, Iori AP, Martino P. Spontaneous Pneumothorax in Patients with Leukemia: First Sign of Invasive Mycosis?. Ann Intern Med. 1993;118:707-708. doi: 10.7326/0003-4819-118-9-199305010-00008
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Published: Ann Intern Med. 1993;118(9):707-708.
Hematology/Oncology, Infectious Disease, Leukemia/Lymphoma, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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