Carol M. Ashton, MD; Louis Wu, MD
Ashton C., Wu L.; Sleep Apnea and the Risk for Perioperative Myocardial Infarction. Ann Intern Med. 1993;119:953. doi: 10.7326/0003-4819-119-9-199311010-00023
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Published: Ann Intern Med. 1993;119(9):953.
The prevalence of obstructive sleep apnea appears to be greater among men with a history of ischemic heart disease . The existence of a causal link between obstructive sleep apnea and myocardial ischemia (in men with preexisting coronary artery disease) or between obstructive sleep apnea and the development of coronary atherosclerosis has not been established; the alternative is that obstructive sleep apnea is a proxy for an as-yet-unknown causal factor. Nevertheless, as Dr. Ortega and colleagues point out, it is reasonable to assume that a man with coexisting sleep apnea syndrome and coronary artery disease might be at a higher risk for perioperative myocardial infarction with noncardiac surgery than a man with only coronary artery disease. This is because recovery room respiratory depression induced by analgesics and residual anesthetics might exacerbate the gas exchange and the hemodynamic aberrations associated with sleep apnea.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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