Keiji Fukuda, MD, MPH; Stephen E. Straus, MD; Ian Hickie, MD, FRANZCP; Michael C. Sharpe, MRCP, MRC Psych; James G. Dobbins, PhD; Anthony Komaroff, MD; International Chronic Fatigue Syndrome Study Group.
Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A, et al. The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study. Ann Intern Med. 1994;121:953-959. doi: 10.7326/0003-4819-121-12-199412150-00009
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Published: Ann Intern Med. 1994;121(12):953-959.
The complexities of the chronic fatigue syndrome and the methodologic problems associated with its study indicate the need for a comprehensive, systematic, and integrated approach to the evaluation, classification, and study of persons with this condition and other fatiguing illnesses. We propose a conceptual framework and a set of guidelines that provide such an approach. Our guidelines include recommendations for the clinical evaluation of fatigued persons, a revised case definition of the chronic fatigue syndrome, and a strategy for subgrouping fatigued persons in formal investigations.
*For a listing of members of the Study Group, see Appendix.
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Infectious Disease, Rheumatology, Chronic Fatigue Syndrome/Fibromyalgia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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