Leilani B. Mercado-Asis, MD, PhD; Edward H. Oldfield, MD; Gordon B. Cutler, MD
Mercado-Asis LB, Oldfield EH, Cutler GB. Pituitary Tumor Hemorrhage in Cushing Disease. Ann Intern Med. 1995;122:189-190. doi: 10.7326/0003-4819-122-3-199502010-00006
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Published: Ann Intern Med. 1995;122(3):189-190.
Spontaneous pituitary hemorrhage and necrosis (pituitary apoplexy) have been reported to occur in 9.5% to 16.6% of pituitary tumors [1-3]. However, pituitary apoplexy rarely develops in patients with Cushing disease. The clinical presentation of pituitary hemorrhage varies from no symptoms to a neurosurgical emergency in which structures in the sellar and parasellar regions are compressed [1-3]. Transient hypopituitarism is common after pituitary apoplexy. Pituitary function may improve either spontaneously [4, 5] or after surgical decompression [6, 7].
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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