Philip J. Podrid, MD
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Podrid PJ. Reevaluation of Amiodarone. Ann Intern Med. 1995;123:809. doi: 10.7326/0003-4819-123-10-199511150-00019
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Published: Ann Intern Med. 1995;123(10):809.
I appreciate the comments made by Drs. Ahmed and Goldman and by Dr. Ahmad. They correctly note other toxicities caused by amiodarone not specifically mentioned in my recent review. I recognize that many side effects were not mentioned, but my intent in the review was not to focus on the many toxicities caused by the drug. Its side-effect profile is well known and has been described in several extensive review articles [1-5]. Rather, my purpose was to critically examine the many reported clinical trials in which this agent has been used. Certainly, before any antiarrhythmic drug is administered, the risks of therapy must be weighed against the benefits. Indeed, the recommendations for amiodarone use were based on both these concerns.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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