Paul A. Lange, MD; James K. Stoller, MD
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Lange P., Stoller J.; Lung Dysfunction and Chronic Liver Disease. Ann Intern Med. 1996;124:369-370. doi: 10.7326/0003-4819-124-3-199602010-00019
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Published: Ann Intern Med. 1996;124(3):369-370.
response: Dr. Brodkin points out the symptomatic and functional improvement that accompanied coil-spring embolization in the patient described by Felt and colleagues . Although the published study did not describe the patient's improvement in dyspnea and exercise capacity, we agree that these unstated benefits shed a more optimistic light on the effect of the embolization. However, the modest improvement in oxygenation (an increase in room air PaO2 from 38 mm Hg to 53 mm Hg) and the persistence of orthodeoxia (despite the deployment of 22 coils in three separate procedures) does justify some reservations. Furthermore, as with liver transplantation for the hepatopulmonary syndrome, longer follow-up periods and larger patient samples among persons having embolization for the hepatopulmonary syndrome (rather than for other conditions such as hereditary hemorrhagic telangiectasia) are needed before the efficacy of embolization can be fully assessed.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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