Cynthia D. Mulrow, MD, MSc; Deborah J. Cook, MD, MSc; Frank Davidoff, MD, Editor
Mulrow CD, Cook DJ, Davidoff F. Systematic Reviews: Critical Links in the Great Chain of Evidence. Ann Intern Med. 1997;126:389-391. doi: 10.7326/0003-4819-126-5-199703010-00008
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Published: Ann Intern Med. 1997;126(5):389-391.
Successful clinical decisions, like most human decisions, are complex creatures . In making them, we draw on information from many sources: primary data and patient preferences, our own clinical and personal experience, external rules and constraints, and scientific evidence (Figure 1). The mix of inputs to clinical decisions varies from moment to moment and from day to day, depending on the decision and the decision makers. In general, however, the proportion of scientific evidence in the mix has grown progressively over the past 150 years or so.
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