Heiner C. Bucher, MD; Gordon H. Guyatt, MD; Richard J. Cook, MD
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Bucher HC, Guyatt GH, Cook RJ. Dietary Calcium and Blood Pressure. Ann Intern Med. 1997;126:492. doi: 10.7326/0003-4819-126-6-199703150-00018
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Published: Ann Intern Med. 1997;126(6):492.
TO THE EDITOR:
Allender and colleagues  investigated the relation of dietary calcium intake and blood pressure in a meta-analysis of randomized, controlled trials. They found that calcium supplementation decreased blood pressure by a greater amount in trials in which the mean blood pressure was greater than 130 mm Hg than in trials in which it was less than 130 mm Hg (change of −1.68 mm Hg [95% CI, −3.18 to −0.18 mm Hg] compared with change of −0.53 mm Hg [CI, −1.56 to 0.49 mm Hg]). We believe the inference that the hypotensive effect of calcium is greater in hypertensive persons is weak. Our reasons follow.
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