Richard J. Mahler, MD
Mahler RJ. Endocrinology: Basic and Clinical Principles. Ann Intern Med. 1997;127:1140. doi: 10.7326/0003-4819-127-12-199712150-00049
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Published: Ann Intern Med. 1997;127(12):1140.
Conn PM, Melmed S, eds. 448 pages. Totowa, NJ: Humana Pr; 1997. $125.00. ISBN 089603349X. Order phone 201-256-1699.
Field of medicine: Endocrinology.
Format: Hardcover book.
Audience: Physicians, scientists, and students who need a high-quality, current reference to the general field of endocrinology, especially those interested in the mechanisms of endocrinologic disease processes and research.
Purpose: To provide a comprehensive knowledge base for the clinical science of endocrinology.
Content: The section entitled “Hormone Secretion and Action” contains a comprehensive discussion of hormone receptors, second messenger systems, and signal transduction mechanisms. It contains a detailed and current review of the mechanisms of steroid hormone action and chapters on the role of cytokines, prostaglandins, and leukotrienes. An interesting chapter links endocrine function and immunity with a detailed consideration of the role of stress. Another section, unique in a clinical endocrinology text, provides insight into immunocytochemical similarities between humans and insects as well as recently described gaseous signaling molecules, which act as second messengers in a variety of mammalian processes and derive from volatile compounds in plant models. The largest section of the book contains chapters on hypothalamic hormones, anterior and posterior pituitary hormones, thyroid hormones, vitamin D and parathyroid hormone, the endocrine pancreas, and the adrenal medulla.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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