Malachi J. McKenna, MD; Rosemarie Freaney, PhD
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McKenna M., Freaney R.; Bone Density and Vitamin D Intoxication. Ann Intern Med. 1998;128:507-508. doi: 10.7326/0003-4819-128-6-199803150-00026
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Published: Ann Intern Med. 1998;128(6):507-508.
TO THE EDITOR:
Hypovitaminosis D in the elderly is a worldwide problem . No evidence suggests that supplementation with parent vitamin D (either low-dose continuous or high-dose intermittent therapy) in the elderly is dangerous , but high doses taken over long periods predispose recipients to hypercalcemia. Even community-dwelling elderly persons benefit from daily administration of calcium (500 mg) and vitamin D (700 IU) . Adams and Lee  report four cases of hypervitaminosis D due to vitamin D intake from multivitamin and dietary supplements. No effort is made to provide even an estimate of vitamin D intake. This is unacceptable at a time when authorities in many countries are recommending vitamin D intakes of 600 to 800 IU daily and when attempts are being made to define the tolerable upper intake level, as mentioned in the editorial accompanying Adams and Lee's report .
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