Scott H. Goodnight, MD; Donald I. Feinstein, MD
Goodnight SH, Feinstein DI. Update in Hematology. Ann Intern Med. 1998;128:545-551. doi: 10.7326/0003-4819-128-7-199804010-00005
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Published: Ann Intern Med. 1998;128(7):545-551.
Recent advances in hematology have focused on thromboembolic diseases and common anemias. Home-based delivery of low-molecular-weight heparin has become more common, and we have gained insight into the natural history of and risks for spontaneous venous thromboembolic disease. Pernicious anemia, previously believed to be more common in men, was found more often in women with previously undiagnosed disease. Iron deficiency in young women may be associated with poor school performance, even before anemia develops. Finally, major relief has been found for patients with multiple myeloma and bone pain.
The major advance seen in thromboembolic disease in the past year was the use of low-molecular-weight heparin as at-home treatment of uncomplicated deep venous thromboses. In addition, new, previously unappreciated risks for the development of thromboembolic disease were elucidated. These risks include increased levels of homocysteine; previous spontaneous thromboembolism; and, to a much lesser degree, the use of estrogen replacement therapy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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