Gary M. Brittenham, MD; Adele L. Franks, MD; Frederick R. Rickles, MD
The Working Group on Research Priorities used a formal nominal group technique to identify and prioritize the specific aims of applied research needed to provide the scientific basis for population screening for iron overload disorders.The most important applied research goal was characterization of the natural history of the relation between genotype and phenotype in hereditary hemochromatosis and other iron overload disorders. Three other important research objectives were development of an optimal approach to screening for iron overload; analyses of the cost-effectiveness of screening; and assessment of the ethical, legal, and social implications of screening. To achieve these specific aims, two research studies were recommended as being of the highest priority: a multicenter, cross-sectional, population-based study of the natural history of iron overload and a multicenter, case–control study of patients with disease manifestations potentially attributable to hereditary hemochromatosis in primary care and subspecialty clinics.
Learn more about subscription options.
Register Now for a free account.
Brittenham GM, Franks AL, Rickles FR. Research Priorities in Hereditary Hemochromatosis. Ann Intern Med. 1998;129:993-996. doi: 10.7326/0003-4819-129-11_Part_2-199812011-00011
Download citation file:
Published: Ann Intern Med. 1998;129(11_Part_2):993-996.
Ethics, Healthcare Delivery and Policy, Prevention/Screening.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only