John K. DiBaise, MD; James V. Huerter, MD; Eamonn M.M. Quigley, MD
The Editors welcome submissions for possible publication in the Letters section. Authors of letters should:
•Include no more than 300 words of text, three authors, and five references
•Type with double-spacing
•Send three copies of the letter, an authors' form signed by all authors, and a cover letter describing any conflicts of interest related to the contents of the letter.
Letters commenting on an Annals article will be considered if they are received within 6 weeks of the time the article was published. Only some of the letters received can be published. Published letters are edited and may be shortened; tables and figures are included only selectively. Authors will be notified that the letter has been received. If the letter is selected for publication, the author will be notified about 3 weeks before the publication date. Unpublished letters cannot be returned.
Annals welcomes electronically submitted letters.
DiBaise JK, Huerter JV, Quigley EM. Sinusitis and Gastroesophageal Reflux Disease. Ann Intern Med. 1998;129:1078. doi: 10.7326/0003-4819-129-12-199812150-00029
Download citation file:
Published: Ann Intern Med. 1998;129(12):1078.
TO THE EDITOR:
Chronic sinusitis that is refractory to medical and surgical therapy presents a considerable clinical challenge. An association between gastroesophageal reflux disease (GERD) and chronic sinusitis has been suggested [1-3]. We reviewed the clinical presentation, diagnostic evaluation, and treatment of patients with chronic refractory sinusitis referred for evaluation of GERD.
Nineteen patients (11 women; mean age, 50.2 years [range, 16 to 76 years]) were evaluated (Table 1). Eighteen had previously undergone sinus surgery. Thirteen (68%) described classic GERD symptoms, and 14 (74%) had possible “atypical” GERD symptoms. On endoscopy (n = 8), 1 patient had erosive esophagitis and 3 had microscopic evidence of GERD. On esophageal manometry (n = 16), the median lower esophageal sphincter pressure was 7.9 mm Hg; 11 patients (69%) had a hypotensive sphincter (<10 mm Hg). All patients except for the patient with erosive esophagitis underwent 24-hour esophageal pH testing by using a single-channel (n = 7) or dual-channel (n = 11; electrodes 15 cm apart) pH catheter. Fourteen patients (78%) had abnormal results (pH < 4.0 more than 9.2% of total time at the distal site or more than 3.3% of total time at the proximal site ).
Learn more about subscription options.
Register Now for a free account.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only