Marina Karmochkine, MD; Michel D. Kazatchkine, MD; Phuc Lehoang, MD, PhD
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Karmochkine M., Kazatchkine M., Lehoang P.; Intravenous Immune Globulin in Autoimmune Uveitis. Ann Intern Med. 1998;129:1078-1079. doi: 10.7326/0003-4819-129-12-199812150-00030
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Published: Ann Intern Med. 1998;129(12):1078-1079.
TO THE EDITOR:
Intravenous immune globulin (IVIg) can be beneficial in several immune-mediated and inflammatory disorders [1, 2]. The administration of IVIg was recently reported to significantly reduce the necessary dose of corticosteroids in patients with severe steroid-dependent asthma, suggesting that IVIg could be used as a steroid-sparing agent in patients with chronic inflammatory conditions .
Birdshot retinochoroidopathy is a chronic bilateral form of posterior uveitis of autoimmune origin strongly associated with HLA-A29. If untreated, it results in photophobia, night blindness, altered visual fields, and, eventually, visual loss . Patients with severe birdshot retinochoroidopathy require long-term therapy with steroids or cyclosporine. The frequent occurrence of side effects, including cataract, osteoporosis, diabetes, and hypertension, can limit therapy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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